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  • Search results for: 'research area metabolism pde'

Search results for: 'research area metabolism pde'

Items 61-70 of 130

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  1. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL
  2. CPI-613
    A4333 CPI-613
     1 Citation
    Target: Pyruvate dehydrogenases (PDH)
    Summary: PDH/α-KGDH inhibitor
      insoluble in H2O; ≥19.45 mg/mL
  3. AGI-5198
    A4339 AGI-5198
     1 Citation
    Summary: IDH1 inhibitor against R132 mutant,selective and cell-permeable
      ≥23.15 mg/mL
  4. S- (+)-Rolipram
    A4349 S- (+)-Rolipram
    Summary: CAMP-specific PDE4 inhibitor
      insoluble in H2O; ≥13.9 mg/mL
  5. Varespladib (LY315920)
    A4356 Varespladib (LY315920)
    Target: Phospholipases
    Summary: HnsPLA inhibitor,potent and selective
  6. JNJ-1661010
    A4361 JNJ-1661010
    Summary: FAAH inhibitor,potent and selective
      Soluble in DMSO
  7. Safinamide Mesylate
    A4368 Safinamide Mesylate
    Summary: MAO-B inhibitor,potent,selective and reversible
  8. Moclobemide (Ro 111163)
    A4370 Moclobemide (Ro 111163)
    Summary: Reversible inhibitor of MAO-A
  9. Ferrostatin-1 (Fer-1)
    A4371 Ferrostatin-1 (Fer-1)
    Target: Ferroptosis
    Summary: Ferroptosis inhibitor, erastin-induced
      ≥149 mg/mL
  10. URB597
    A4372 URB597
    Summary: FAAH inhibitor,potent and selective
      insoluble in H2O; ≥16.9 mg/mL

Items 61-70 of 130

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Category
  1. Proteases 1 item
  2. Apoptosis 1 item
  3. Metabolism 100item
  4. Tyrosine Kinase 1 item
  5. DNA Damage/DNA Repair 2item
  6. PI3K/Akt/mTOR Signaling 2item
  7. Microbiology & Virology 2item
  8. GPCR/G protein 3item
  9. Stem Cell 1 item
  10. Membrane Transporter/Ion Channel 3item
  11. Cancer Biology 1 item
  12. Endocrinology and Hormones 1 item
  13. Neuroscience 3item
  14. Others 9item
  15. Immunology/Inflammation 4item
  16. Vitamin D Related 1 item
Specificity
  1. Selective 46item
  2. Non-Selective 1 item
Reversibility
  1. Reversible 1 item
  2. Irreversible 4item
Target
  1. Acyl coenzyme A: cholesterol acyltransferases 1 item
  2. Factor Xa 1 item
  3. Phosphodiesterases (PDEs) 13item
  4. RARs 1 item
  5. Estrogen and Related Receptors 1 item
  6. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  7. AMPK 1 item
  8. Cytochrome P450 (CYP450) 4item
  9. Ferroptosis 1 item
  10. HMG-CoA Reductases 3item
  11. SGLT 1 item
  12. DGAT 2item
  13. Insulin and Insulin-like Receptors 1 item
  14. Pyruvate dehydrogenases (PDH) 1 item
  15. CETP 2item
  16. Fatty-acid-binding proteins (FABPs) 1 item
  17. Folate Analogue 1 item
  18. IDH2 1 item
  19. Nampt 1 item
  20. Carbonic Anhydrases 3item
  21. Histamine H1 Receptors 1 item
  22. Phospholipases 1 item
  23. Catechol O-Methyltransferase (COMT) 1 item
  24. Hydroxylases 1 item
  25. ATGL 1 item
  26. FPTase 1 item
  27. PPAR 1 item
  28. FAAH 1 item
  29. carnitine reabsorption 1 item
  30. TRPC channel 1 item
Reported Experiments
  1. Animal Experiments 61item
  2. Cell Experiments 51item
Related Disease
  1. Acne 1 item
  2. Acute Kidney Injury 1 item
  3. Acute Myelogenous Leukemia 1 item
  4. Bladder Cancer 1 item
  5. Bladder Carcinoma 1 item
  6. Brain Injuries Studies 1 item
  7. Breast Cancer 5item
  8. Cancer 14item
  9. Cervical Cancer 1 item
  10. Cocaine-Related Disorders 1 item
  11. Diabetes 1 item
  12. Dyslipidemia 2item
  13. Erectile Dysfunction 3item
  14. HIV 1 item
  15. Hypercholesterolemia 2item
  16. Inflammation 1 item
  17. Inflammatory Diseases 2item
  18. Kidney Injury Studies 1 item
  19. Leukemia 2item
  20. Lung Cancer 2item
  21. Lymphoma 3item
  22. Melanoma 2item
  23. Neuroblastoma 3item
  24. Neurocognitive Disorders 1 item
  25. Obsessive-Compulsive Disorder 1 item
  26. Prostate Cancer 2item
  27. Psoriasis 2item
  28. Psoriasis Vulgaris 1 item
  29. Pulmonary Arterial Hypertension 1 item
  30. Rheumatoid Arthritis 2item
  31. Schizophrenia 2item
  32. Type 2 Diabetes 4item