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S- (+)-Rolipram

Catalog No.
A4349
CAMP-specific PDE4 inhibitor
Grouped product items
Size Price Stock Qty
10mM (in 1mL DMSO)
Special Price $24.75 Regular Price $55.00
In stock
5mg
Special Price $22.50 Regular Price $50.00
In stock
10mg
Special Price $38.25 Regular Price $85.00
In stock
25mg
Special Price $85.50 Regular Price $190.00
In stock
50mg
Special Price $148.50 Regular Price $330.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt275.34
Cas No.85416-73-5
FormulaC16H21NO3
Solubilityinsoluble in H2O; ≥13.9 mg/mL in DMSO; ≥20.76 mg/mL in EtOH with gentle warming and ultrasonic
Chemical Name(4S)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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