4-Chlorophenylguanidine hydrochloride
Catalog No.
A4445
Urokinase inhibitor, potent and specific
Featured Products
4-Chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].
Urokinase is a serine protease. Its primary physiological substrate is plasminogen, which is an inactive form of plasmin. Urokinase plays an important role in vascular diseases and cancer.
4-Chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with Ki value of 6.07 μM and 120 μM, respectively [1].
Reference:
[1]. Yang H, Henkin J, Kim KH, et al. Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. J Med Chem, 1990, 33(11): 2956-2961.
| Physical Appearance | White crystalline solid |
| Storage | Store at RT |
| M.Wt | 206.07 |
| Cas No. | 14279-91-5 |
| Formula | C7H8ClN3·HCl |
| Solubility | Soluble to 100 mM in H2O |
| Chemical Name | 2-(4-chlorophenyl)guanidine;hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | C1=CC(=CC=C1N=C(N)N)Cl.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
