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Signaling Pathways

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  1. PD-1/PD-L1 inhibitor 2
    B6023 PD-1/PD-L1 inhibitor 2
    Target: PD-1/PD-L1 interaction
    Summary: PD-1/PD-L1 interaction inhibitor
      ≥42 mg/mL
  2. AZ 10417808
    A4416 AZ 10417808
    Target: Caspases
    Summary: Caspase-3 inhibitor,selective non-peptide
      <10.86 mg/mL
  3. Ivachtin
    A4417 Ivachtin
    Summary: Caspase-3 inhibitor
      soluble in DMSO or DMF
  4. PETCM
    A4420 PETCM
    Summary: Caspase-3 activator
  5. Ac-IEPD-AFC
    A4418 Ac-IEPD-AFC
    Summary: Recognition motif for serine protease granzyme B
  6. R18
    A4446 R18
    Summary: 14.3.3 proteins Antagonist
      Soluble to 1 mg/mL
  7. 2,3-DCPE hydrochloride
    A4447 2,3-DCPE hydrochloride
    Target: Apoptosis Inducers
    Summary: Bcl-XL protein expression downregulator
      <30.06 mg/mL
  8. Actinomycin D
    A4448 Actinomycin D
     15 Citation
    Summary: RNA polymerase inhibitor
      ≥62.75 mg/mL
  9. C 75
    A4449 C 75
    Summary: Fatty acid synthase (FAS) inhibitor
      ≥22.5 mg/mL
  10. CHM 1
    A4450 CHM 1
    Summary: Tubulin polymerization inhibitor
      <7.08 mg/mL

Items 1-10 of 225

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  1. Category Apoptosis Remove This Item
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Category
  1. Caspase 31item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 43item
  4. Bax 6item
  5. Bcl-2 Family 30item
  6. Bcl-xL 8item
  7. c-RET 9item
  8. IAP 9item
  9. KEAP1-Nrf2 10item
  10. MDM2 13item
  11. p53 38item
  12. PC-PLC 4item
  13. PKD 5item
  14. RasGAP (Ras- P21) 1 item
  15. Survivin 2item
  16. Thymidylate Synthase 5item
  17. TNF-α 12item
  18. Other Apoptosis 7item
  19. APC 1 item
  20. PD-1/PD-L1 interaction 3item
  21. ASK1 3item
  22. PAR4 2item
  23. Apoptosis 6item
  24. MDM-2/p53 1 item
Specificity
  1. Selective 51item
Reversibility
  1. Reversible 1 item
  2. Irreversible 9item
Target
  1. Caspases 14item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 3item
  5. Bcl-2 9item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 3item
  9. MDM2 2item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 7item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 2item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. Aminopeptidases 1 item
  21. RIP kinases 1 item
  22. PD-1/PD-L1 interaction 1 item
  23. Topoisomerases 1 item
  24. Survivin 1 item
  25. Dehydrogenase 1 item
  26. Autophagy 1 item
  27. Mixed lineage kinase domain-like protein (MLKL) 1 item
  28. COX 1 item
  29. iNOS 1 item
  30. TRP Channel 1 item
  31. Apoptosis Inducers 1 item
  32. angiogenesis 1 item
  33. c-RET 1 item
  34. FPTase 1 item
  35. Bfl-1 1 item
  36. p53-MDM2 interaction 2item
  37. p53 7item
  38. cysteine protease 1 item
  39. Nrf2/ARE signal 1 item
  40. PPAR 1 item
  41. HDM2 ubiquitin ligase 1 item
  42. PC-PLC 2item
  43. AAT 1 item
  44. HIV 1 item
  45. Histone Acetyltransferases (HATs) 1 item
  46. Telomerases 1 item
  47. Tyrosinases 1 item
  48. HSP70 1 item
  49. Ubiquitin E3 Ligases 1 item
  50. MDMX 1 item
  51. p21 1 item
  52. DHFR 1 item
  53. GARFT 1 item
  54. PKD 1 item
  55. MCL1 1 item
  56. Bcl-w 1 item
  57. Bax 1 item
  58. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 69item
  2. Cell Experiments 58item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 9item
  5. Cancer 46item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 4item
  9. Colorectal Cancer 3item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 3item
  15. Lymphoma 4item
  16. Melanoma 2item
  17. Multiple Myeloma 2item
  18. Myelofibrosis 1 item
  19. Myeloma 1 item
  20. Neuroblastoma 1 item
  21. Non-small Cell Lung Cancer 4item
  22. Ovarian Cancer 1 item
  23. Pain Relief 1 item
  24. Pancreatic Cancer 3item
  25. Pentacyclic Triterpenoid 1 item
  26. Prostate Cancer 5item
  27. Pulmonary Fibrosis 1 item
  28. Rheumatoid Arthritis 1 item
  29. Soft Tissue Sarcoma 1 item
  30. Testicular Cancer 1 item