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Signaling Pathways

Signaling Pathways

A4452 Mitomycin C

3 Citation

Summary: Inhibits DNA synthesis,antibiotic and antitumor agent

insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
B2092 Doxifluridine

Summary: oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU)

insoluble in EtOH; ≥10 mg/mL
A8176 Apicidin

2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Potent HDAC inhibitor

soluble in DMSO or ethanol
A8177 PAC-1

1 Citation

Target: Caspases

Summary: Procaspase-3 activator

insoluble in H2O; ≥13.4 mg/mL
A4221 YM155

2 Citation

Target: Survivin

Summary: Survivin suppressant,apoptosis inhibitor

≥22.15 mg/mL
A4224 GDC-0152

2 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: IAP antagonist,potent amd samll-molecule

≥24.95 mg/mL
A4234 TW-37

1 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1

insoluble in H2O; ≥19.75 mg/mL
A4200 Apogossypolone (ApoG2)

2 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor,nonpeptidic small molecule

≥24.55 mg/mL
A8815 SM-164

8 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: Anticancer agent

≥56.07 mg/mL