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Signaling Pathways

Items 1-10 of 58

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  1. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  2. Bax inhibitor peptide V5
    A4461 Bax inhibitor peptide V5
    Target: Bax
    Summary: Bax inhibitor
      ≥29.35 mg/mL
  3. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  4. PhiKan 083
    A4481 PhiKan 083
    Target: p53
    Summary: p53 stabilizer
      <13.74 mg/mL
  5. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  6. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  7. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  8. Nutlin-3b
    A2005 Nutlin-3b
    Target: p53-MDM2 interaction
    Summary: MDM2/p53 inhibitor
  9. WEHI-539 hydrochloride
    A8634 WEHI-539 hydrochloride
     1 Citation
    Summary: Bcl-xL inhibitor,high affinity and selective
      ≥28.55 mg/mL
  10. CID 755673
    A8678 CID 755673
    Target: PKD
    Summary: PKD inhibitor

Items 1-10 of 58

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  1. Category Apoptosis Remove This Item
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Category
  1. Caspase 8item
  2. Apoptosis Inducers 9item
  3. Bax 2item
  4. Bcl-2 Family 15item
  5. Bcl-xL 4item
  6. c-RET 3item
  7. IAP 1 item
  8. KEAP1-Nrf2 3item
  9. MDM2 4item
  10. p53 10item
  11. PC-PLC 2item
  12. PKD 1 item
  13. Thymidylate Synthase 2item
  14. TNF-α 4item
Specificity
  1. Selective 25item
Reversibility
  1. Irreversible 6item
Target
  1. Caspases 7item
  2. Histone Deacetylases (HDACs) 1 item
  3. Inhibitor of apoptosis proteins (IAP) 1 item
  4. Bcl-2 8item
  5. Raf 2item
  6. Aurora Kinases 1 item
  7. Bcl-xl 3item
  8. MDM2 1 item
  9. VEGFR 2item
  10. PDGFR 3item
  11. c-Kit 2item
  12. RET 1 item
  13. Mcl-1 5item
  14. Thymidylate Synthase 1 item
  15. Bcr-Abl 1 item
  16. Nrf2 1 item
  17. Sir2-like Family Deacetylases (Sirtuins) 1 item
  18. Aminopeptidases 1 item
  19. Topoisomerases 1 item
  20. Autophagy 1 item
  21. TRP Channel 1 item
  22. angiogenesis 1 item
  23. c-RET 1 item
  24. FPTase 1 item
  25. Bfl-1 1 item
  26. p53-MDM2 interaction 2item
  27. p53 7item
  28. cysteine protease 1 item
  29. Nrf2/ARE signal 1 item
  30. PPAR 1 item
  31. HDM2 ubiquitin ligase 1 item
  32. PC-PLC 2item
  33. AAT 1 item
  34. HIV 1 item
  35. Histone Acetyltransferases (HATs) 1 item
  36. Telomerases 1 item
  37. Tyrosinases 1 item
  38. HSP70 1 item
  39. Ubiquitin E3 Ligases 1 item
  40. MDMX 1 item
  41. p21 1 item
  42. DHFR 1 item
  43. GARFT 1 item
  44. PKD 1 item
  45. MCL1 1 item
  46. Bcl-w 1 item
  47. Bax 1 item
  48. NS3/4a Proteases 1 item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Breast Cancer 5item
  3. Cancer 28item
  4. Chronic Lymphocytic Leukemia 1 item
  5. Chronic Myeloproliferative Disorders 1 item
  6. Colon Cancer 1 item
  7. Colorectal Cancer 2item
  8. Glioblastoma 1 item
  9. HCV 1 item
  10. Lymphoma 3item
  11. Melanoma 1 item
  12. Multiple Myeloma 1 item
  13. Myelofibrosis 1 item
  14. Pain Relief 1 item
  15. Pancreatic Cancer 1 item
  16. Pentacyclic Triterpenoid 1 item
  17. Prostate Cancer 3item
  18. Pulmonary Fibrosis 1 item
  19. Soft Tissue Sarcoma 1 item