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Signaling Pathways

Items 1-10 of 66

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  1. Flumazenil
    A2917 Flumazenil
    Target: GABAA Receptors
    Summary: Benzodiazepine antagonist
      insoluble in H2O; insoluble in EtOH; ≥30.38 mg/mL
  2. Etomidate
    A1958 Etomidate
    Target: GABAA Receptors
    Summary: General anesthetic with GABA modulatory and GABA-mimetic actions
      insoluble in H2O; ≥12.212 mg/mL
  3. TRAM-34
    A1888 TRAM-34
    Target: Calcium-Activated Potassium (KCa) Channels
    Summary: KCa3.1 blocker,potent and highly selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  4. Bumetanide
    A1855 Bumetanide
    Target: Na /K /Cl- Symporters (NKCCs)
    Summary: NKCC cotransporter inhibitor
      insoluble in H2O; ≥36.37 mg/mL
  5. Zonisamide
    A5354 Zonisamide
    Target: Voltage-gated Sodium (NaV) Channels|Voltage-gated Calcium Channels (CaV)|Carbonic Anhydrases|Calcium-Activated Potassium (KCa) Channels
    Summary: Antiepileptic with anticonvulsant and mechanistic effect
      insoluble in H2O; ≥8.35 mg/mL
  6. AMG-517
    A1174 AMG-517
    Target: TRP Channel
    Summary: TRPV1 antagonist,potent and highly selective
      ≥21.5 mg/mL
  7. Omecamtiv mecarbil
    A8349 Omecamtiv mecarbil
    Target: Myosin
    Summary: Cardiac myosin activator
  8. Furosemide
    A8435 Furosemide
    Target: Na /K /Cl- Symporters (NKCCs)|GABAA Receptors
    Summary: GABAA receptors antagonist
  9. Gabapentin
    A8436 Gabapentin
    Summary: GABA enhancer
  10. Riluzole
    A8513 Riluzole
    Target: Voltage-gated Sodium (NaV) Channels|glutamate release
    Summary: Sodium channel protein inhibitor
      ≥23.4 mg/mL

Items 1-10 of 66

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Category
  1. AMPAR 1 item
  2. ATPase 9item
  3. Calcium Channel 11item
  4. CFTR 3item
  5. Chloride Channels 1 item
  6. GABA Receptor 6item
  7. MCT2 1 item
  8. Na+/Ca2+ Exchanger 1 item
  9. NKCC 2item
  10. NMDA Receptor 2item
  11. P2X purinergic receptor 2item
  12. P-gp 2item
  13. Potassium Channel 9item
  14. Sodium Channel 11item
  15. TRP Channel 3item
  16. TRPV1 1 item
  17. Other Channel Modulators 1 item
Specificity
  1. Selective 36item
Reversibility
  1. Reversible 4item
Target
  1. Myosin II ATPases 1 item
  2. Voltage-gated Potassium (KV) Channels 2item
  3. P-glycoprotein (P-gp) 2item
  4. GABAB Receptors 1 item
  5. Voltage-gated Sodium (NaV) Channels 9item
  6. NMDA Receptors 2item
  7. CFTR 2item
  8. Cytochrome P450 (CYP450) 1 item
  9. DNA Methyltransferases 1 item
  10. Ca2 /calmodulin-dependent protein kinases (CaMKs) 1 item
  11. Voltage-gated Calcium Channels (CaV) 8item
  12. Monocarboxylate transporters (MCTs) 1 item
  13. Myosin light chain kinases (MLCKs) 1 item
  14. P2X Receptors 1 item
  15. Carbonic Anhydrases 1 item
  16. Calcium-activated chloride channels (CaCC) 1 item
  17. GPR35 1 item
  18. Na /K ATPases 2item
  19. Na /K /Cl- Symporters (NKCCs) 2item
  20. GABAA Receptors 3item
  21. TRP Channel 2item
  22. Ionophores 1 item
  23. Calcium-Activated Potassium (KCa) Channels 2item
  24. cAMP 1 item
  25. Sulfonylurea receptors 1 item
  26. Inward Rectifier Potassium (Kir) Channels 3item
  27. Na /Ca2 Exchangers (NCXs) 1 item
  28. Myosin 1 item
  29. 5-HT receptors 1 item
  30. sodium channel 2item
  31. TRPV 1 item
  32. NTPDases 1 item
  33. Calmodulins 1 item
  34. TRPA 1 item
  35. F1 Fo-ATPase 1 item
  36. AMPA Receptors 1 item
  37. mitochondrial pyruvate carrier (MPC) 1 item
  38. Protein Tyrosine Phosphatases 1 item
  39. alkaline phosphatases 1 item
  40. ATPases 1 item
  41. benzodiazepine receptor 1 item
  42. glutamate release 1 item
  43. NHE 1 item
  44. GABAA receptor 1 item
Related Disease
  1. Anesthesia 2item
  2. Breast Cancer 1 item
  3. Cancer 5item
  4. Epilepsy 3item
  5. Glioma 1 item
  6. Heart Failure 3item
  7. Lymphoma 1 item
  8. Non-small Cell Lung Cancer 1 item
  9. Non-small Cell Lung Carcinoma 1 item
  10. Ovarian Cancer 1 item
  11. Type 2 Diabetes 5item