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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

10 Items

per page
  1. TH-302
    A3872 TH-302
    Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
      ≥22.45 mg/mL
  2. Irinotecan HCl Trihydrate
    B2293 Irinotecan HCl Trihydrate
    Target: Topoisomerases
    Summary: Topoisomerase 1 inhibitor
      ≥23.1 mg/mL
  3. Pirarubicin
    B2295 Pirarubicin
     1 Citation
    Target: Topoisomerases
    Summary: Topoisomerase II inhibitor;anthracycline antibiotic
      insoluble in H2O; insoluble in EtOH; ≥7.65 mg/mL
  4. Beta-Lapachone
    B2290 Beta-Lapachone
    Target: Topoisomerases
    Summary: DNA topoisomerase I inhibitor,selective
      insoluble in H2O; ≥10.85 mg/mL
  5. Doxorubicin (Adriamycin) HCl
    A1832 Doxorubicin (Adriamycin) HCl
     2 Citation
    Target: Topoisomerases
    Summary: Antitumour antibiotic,inhibits TOPO II.
      ≥29 mg/mL
  6. Camptothecin
    A2877 Camptothecin
     1 Citation
    Target: Topoisomerases
    Summary: Topoisomerase I inhibitor,prototypic
      insoluble in H2O; insoluble in EtOH; ≥8.7 mg/mL
  7. Etoposide
    A1971 Etoposide
     4 Citation
    Target: Topoisomerases
    Summary: Topo II inhibitor
      ≥29.45 mg/mL
  8. Epirubicin HCl
    A2451 Epirubicin HCl
    Target: Topoisomerases
    Summary: Antibiotic antitumor agent
      ≥29.00 mg/mL
  9. (S)-10-Hydroxycamptothecin
    B4745 (S)-10-Hydroxycamptothecin
    Target: Topoisomerases
    Summary: inhibitor of topoisomerase I
      ≥23.8 mg/mL
  10. Ellipticine
    B7382 Ellipticine
    Target: Topoisomerases
    Summary: DNA topoisomerase II inhibitor
      ≥24.6 mg/mL

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