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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

A3320 CO-1686 (AVL-301)

1 Citation

Target: EGFR

Summary: EGFR inhibitor

≥27.8 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
B1104 AZD-9291

1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL
A8366 ARRY-380

Target: HER2

Summary: Tyrosine kinase HER2 and p95-HER2 inhibitor

≥28.5 mg/mL
A8375 AZD8931 (Sapitinib)

Target: EGFR|ErbB

Summary: ErbB inhibitor

≥23.7 mg/mL
A4139 AG-490

3 Citation

Target: EGFR|JAK

Summary: JAK2/EGFR inhibitor

insoluble in H2O; ≥14.7 mg/mL
A8218 Lapatinib

2 Citation

Target: ErbB

Summary: EGFR/HER2 inhibitor,potent,selective and reversible

≥29.05 mg/mL
A8219 Gefitinib (ZD1839)

3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A8247 Afatinib (BIBW2992)

1 Citation

Target: EGFR

Summary: Irreversible EGFR/HER2 inhibitor

≥24.3 mg/mL
A2412 CP-724714

Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R

Summary: HER2 inhibitor,potent and selective

≥23.5 mg/mL