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MEK1/2

MEK1/2, also known as MAPKK (mitogen-activated protein kinase kinase), is a kinase enzyme which phosphorylates MAPK (mitogen-activated protein kinase).

Items 21-30 of 37

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  1. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  2. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  3. PD318088
    A5707 PD318088
    Target: MEK
    Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive
      ≥28.05 mg/mL
  4. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  5. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  6. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  7. GDC-0994
    B5817 GDC-0994
     2 Citation
    Summary: ERK1/2 inhibitor
      ≥44.1 mg/mL
  8. RO5126766(CH5126766)
    B5820 RO5126766(CH5126766)
    Summary: Raf/MEK dual inhibitor
      insoluble in H2O; insoluble in EtOH; ≥35.7 mg/mL
  9. SCH772984 TFA
    B5867 SCH772984 TFA
    Summary: ERK1/2 inhibitor
      ≥26.1 mg/mL
  10. SCH772984 HCl
    B5866 SCH772984 HCl
    Summary: ERK1/2 inhibitor
      ≥23.5 mg/mL

Items 21-30 of 37

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