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MEK1/2

MEK1/2, also known as MAPKK (mitogen-activated protein kinase kinase), is a kinase enzyme which phosphorylates MAPK (mitogen-activated protein kinase).

Items 1-10 of 13

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  1. PD98059
    A1663 PD98059
     9 Citation
    Target: MEK
    Summary: MEK inhibitor,selective and reversible
      insoluble in EtOH; insoluble in H2O; ≥40.23 mg/mL
  2. SL-327
    A1894 SL-327
     1 Citation
    Target: MEK
    Summary: Selective MEK1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.75 mg/mL
  3. PD184352 (CI-1040)
    A1792 PD184352 (CI-1040)
    Target: MEK
    Summary: Selective MEK inhibitor
      ≥47.9 mg/mL
  4. U0126-EtOH
    A1337 U0126-EtOH
     10 Citation
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.33 mg/mL
  5. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  6. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  7. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  8. AZD8330
    A8374 AZD8330
    Target: MEK
    Summary: MEK 1/2 inhibitor
      ≥23.05 mg/mL
  9. TAK-733
    B1621 TAK-733
    Target: MEK
    Summary: MEK allosteric site inhibitor
      ≥25.2 mg/mL
  10. Refametinib
    B1267 Refametinib
    Target: MEK
    Summary: MEK 1/ MEK 2 inhibitor
      insoluble in H2O; ≥151.8 mg/mL

Items 1-10 of 13

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