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P-gp

P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.

A3859 Tariquidar methanesulfonate, hydrate

Target: P-glycoprotein (P-gp)

Summary: P-glycoprotein inhibitor, potent and selective

insoluble in H2O; insoluble in EtOH; ≥56.2 mg/mL
A3956 Zosuquidar

Target: P-glycoprotein (P-gp)|Cytochrome P450 (CYP450)

Summary: MDR modulator

Soluble in DMSO
A8208 Tariquidar

2 Citation

Target: P-glycoprotein (P-gp)

Summary: P-glycoprotein inhibitor,potent and non-competitive

insoluble in H2O; insoluble in EtOH; ≥16.17 mg/mL
A8549 LY335979 (Zosuquidar 3HCL)

1 Citation

Target: P-glycoprotein (P-gp)

Summary: Pgp (P-glycoprotein) inhibitor

insoluble in EtOH; ≥17.1 mg/mL