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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Items 11-18 of 18

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  1. Avanafil
    A4334 Avanafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.6 mg/mL
  2. Cilostazol
    A4337 Cilostazol
    Summary: PDE3 inhibitor
      insoluble in H2O; ≥15.4 mg/mL
  3. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  4. Aminophylline
    A4346 Aminophylline
    Target: Phosphodiesterases (PDEs)
    Summary: Pan-PDE inhibitor
      ≥13.48 mg/mL
  5. S- (+)-Rolipram
    A4349 S- (+)-Rolipram
    Summary: CAMP-specific PDE4 inhibitor
      insoluble in H2O; ≥13.9 mg/mL
  6. AN-2728
    A3178 AN-2728
    Summary: PDE4 inhibitor,anti-inflammatory compound
      insoluble in H2O; ≥12.55 mg/mL
  7. BRL 50481
    B6988 BRL 50481
    Target: Phosphodiesterases (PDEs)
    Summary: PDE7 inhibitor,potent and selective
      Soluble in DMSO
  8. Etazolate hydrochloride
    B6304 Etazolate hydrochloride
     2 Citation
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-4 inhibitor and selective GABA-A receptor modulator
      ≥7.75 mg/mL

Items 11-18 of 18

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