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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

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  1. ML-030
    C4805 ML-030
    Summary: PDE4 inhibitor
      ≤5 mg/mL
  2. Sp-Cyclic AMPS (sodium salt)
    C4942 Sp-Cyclic AMPS (sodium salt)
    Summary: cAMP derivative used to bind PDE10 GAF domain
      ≤25 mg/mL
  3. Ibudilast
    C5183 Ibudilast
    Summary: inhibitor of PDE4
  4. T 0156 hydrochloride
    B5162 T 0156 hydrochloride
    Summary: inhibitor of phosphodiesterase type 5 (PDE5)
      <14.59 mg/mL
  5. Piclamilast
    B5630 Piclamilast
    Summary: PDE4 inhibitor
      <38.12 mg/mL
  6. TC-E 5005
    B5642 TC-E 5005
    Summary: PDE10A inhibitor
  7. Irsogladine
    B1593 Irsogladine
    Summary: PDE4 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥12.80 mg/mL
  8. Udenafil
    B3439 Udenafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; ≥117.2 mg/mL
  9. Ro 20-1724
    B6294 Ro 20-1724
    Summary: PDE4 inhibitor
      insoluble in H2O; ≥4.88 mg/mL
  10. Trequinsin hydrochloride
    B7022 Trequinsin hydrochloride
    Summary: PDE3 inhibitor
      Soluble in DMSO

Items 31-40 of 54

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