PDE
PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.
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B7206 IBMX1 CitationSummary: Phosphodiesterase inhibitor -
B6988 BRL 50481Target: Phosphodiesterases (PDEs)Summary: PDE7 inhibitor,potent and selective
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B7162 CP 80633Summary: PDE4 inhibitor
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B7257 MesopramSummary: PDE4 inhibitor, orally active
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B7539 CDP 840 hydrochlorideSummary: PDE4 inhibitor,potent and selective
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B7599 Gisadenafil besylateSummary: PDE5 inhibitor
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B7673 BC 11-38Summary: Selective PDE11 inhibitor
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B6301 MY-5445Summary: PDE5 inhibitor
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B6304 Etazolate hydrochloride2 CitationTarget: Phosphodiesterases (PDEs)Summary: PDE-4 inhibitor and selective GABA-A receptor modulator
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B6500 Cilostamide1 CitationSummary: type III phosphodiesterase (PDE3) inhibitor