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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

9 Items

per page
  1. Apremilast (CC-10004)
    A4317 Apremilast (CC-10004)
    Target: Phosphodiesterases (PDEs)
    Summary: PDE4 inhibitor
      ≥23.05 mg/mL
  2. Vardenafil HCl Trihydrate
    A4323 Vardenafil HCl Trihydrate
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor, potent and selective
      ≥13.3 mg/mL
  3. PF-2545920
    A4325 PF-2545920
    Target: Phosphodiesterases (PDEs)
    Summary: PDE10A inhibitor,potent and selective
      insoluble in H2O; ≥19.35 mg/mL
  4. Tadalafil
    A4327 Tadalafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.6 mg/mL
  5. Avanafil
    A4334 Avanafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥17.6 mg/mL
  6. Pimobendan
    A4340 Pimobendan
    Target: Phosphodiesterases (PDEs)
    Summary: Selective PDE3 inhibitor.Ca2+ channel sensitizer
      insoluble in H2O; ≥16.2 mg/mL
  7. Vinpocetine
    B2276 Vinpocetine
    Target: Phosphodiesterases (PDEs)
    Summary: PDE inhibitor
      ≥2.59 mg/mL
  8. BRL 50481
    B6988 BRL 50481
    Target: Phosphodiesterases (PDEs)
    Summary: PDE7 inhibitor,potent and selective
      Soluble in DMSO
  9. Etazolate hydrochloride
    B6304 Etazolate hydrochloride
     2 Citation
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-4 inhibitor and selective GABA-A receptor modulator
      ≥7.75 mg/mL

9 Items

per page