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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

Items 1-10 of 12

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  1. Ridaforolimus (Deforolimus, MK-8669)
    B1639 Ridaforolimus (Deforolimus, MK-8669)
    Target: mTOR
    Summary: MTOR inhibitor
      ≥49.5 mg/mL
  2. WAY-600
    B1641 WAY-600
    Target: mTOR
    Summary: MTOR inhibitor
      ≥12.38 mg/mL
  3. INK 128 (MLN0128)
    A8551 INK 128 (MLN0128)
     4 Citation
    Target: mTOR
    Summary: MTOR(TORC-1/-2) inhibitor,potent and selective
      insoluble in H2O; ≥15.45 mg/mL
  4. GSK2126458
    A8556 GSK2126458
     1 Citation
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor
      ≥25.3 mg/mL
  5. WYE-125132 (WYE-132)
    B1642 WYE-125132 (WYE-132)
    Target: mTOR
    Summary: ATP-competitive mTOR inhibitor, highly potent
      insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
  6. Torin 2
    B1640 Torin 2
     1 Citation
    Target: mTOR|DNA-PK|ATM/ATR
    Summary: MTOR inhibitor,highly potent and selective
      ≥21.6 mg/mL
  7. Rapamycin (Sirolimus)
    A8167 Rapamycin (Sirolimus)
     15 Citation
    Target: mTOR
    Summary: Original antifungal antibiotic
      ≥45.7 mg/mL
  8. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL
  9. AZD8055
    A8214 AZD8055
     2 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥23.3 mg/mL
  10. Torin 1
    A8312 Torin 1
     7 Citation
    Target: mTOR
    Summary: MTOR inhibitor,potent and selective

Items 1-10 of 12

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