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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 11-20 of 20

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  1. BAY 80-6946 (Copanlisib)
    B2178 BAY 80-6946 (Copanlisib)
     1 Citation
    Target: PI3K
    Summary: PI3K inhibitor
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  2. AS-252424
    B2180 AS-252424
    Target: Akt|PI3K
    Summary: PI3Kγ inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
  3. VS-5584 (SB2343)
    A3927 VS-5584 (SB2343)
    Target: PI3K|mTOR
    Summary: MTOR/P13K inhibitor,potent and selective
      insoluble in H2O; ≥17.7 mg/mL
  4. CAL-101 (Idelalisib, GS-1101)
    A3005 CAL-101 (Idelalisib, GS-1101)
     2 Citation
    Target: PI3K
    Summary: PI3K inhibitor
  5. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  6. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  7. LY3023414
    B6099 LY3023414
    Target: Akt|PI3K|mTOR|DNA-PK
    Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
      ≥40.6 mg/mL
  8. Acalisib (GS-9820)
    B5831 Acalisib (GS-9820)
    Target: PI3K
    Summary: PI3Kδ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
  9. HS-173
    B4492 HS-173
    Target: PI3K
    Summary: novel PI3K inhibitor
      ≥21.1 mg/mL
  10. PI-3065
    B4660 PI-3065
    Target: PI3K
    Summary: P110δkinase inhibitor
      ≥22.7 mg/mL

Items 11-20 of 20

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