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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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  1. PIK-75
    A2080 PIK-75
    Summary: Inhibitor of PI3K isoform p110α
      insoluble in H2O; insoluble in EtOH; ≥8.15 mg/mL
  2. IC-87114
    A2065 IC-87114
    Summary: PI3Kδ inhibitor
  3. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
  4. PIK-93
    A5449 PIK-93
    Summary: PI3Kγ/PI4KIIIβ/PI3Kα inhibitor
      insoluble in H2O; ≥19.5 mg/mL
  5. AZD6482
    A5478 AZD6482
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent and selective
      insoluble in H2O; ≥20.4 mg/mL
  6. SAR245409 (XL765)
    A5634 SAR245409 (XL765)
    Summary: mTOR/PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  7. Duvelisib (IPI-145, INK1197)
    A1720 Duvelisib (IPI-145, INK1197)
    Target: PI3K
    Summary: PI3K-δ/PI3K-γ inhibitor
      ≥20.84 mg/mL
  8. BYL-719
    A8346 BYL-719
     1 Citation
    Target: PI3K
    Summary: Selective PI3Kα inhibitor
      ≥22.07 mg/mL
  9. A66
    A8354 A66
    Target: PI3K
    Summary: P110α inhibitor
      insoluble in H2O; ≥19.7 mg/mL
  10. NVP-BGT226
    A8488 NVP-BGT226
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor,selective and novel
      insoluble in EtOH; insoluble in H2O; ≥16.28 mg/mL

Items 11-20 of 62

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