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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 11-20 of 21

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  1. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  2. TGX-221
    A2681 TGX-221
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent,selective and ATP competitive
      insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
  3. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
  4. Duvelisib (IPI-145, INK1197)
    A1720 Duvelisib (IPI-145, INK1197)
    Target: PI3K
    Summary: PI3K-δ/PI3K-γ inhibitor
      ≥20.84 mg/mL
  5. BYL-719
    A8346 BYL-719
     1 Citation
    Target: PI3K
    Summary: Selective PI3Kα inhibitor
      ≥22.07 mg/mL
  6. A66
    A8354 A66
    Target: PI3K
    Summary: P110α inhibitor
      insoluble in H2O; ≥19.7 mg/mL
  7. LY3023414
    B6099 LY3023414
    Target: Akt|PI3K|mTOR|DNA-PK
    Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
      ≥40.6 mg/mL
  8. Acalisib (GS-9820)
    B5831 Acalisib (GS-9820)
    Target: PI3K
    Summary: PI3Kδ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL
  9. HS-173
    B4492 HS-173
    Target: PI3K
    Summary: novel PI3K inhibitor
      ≥21.1 mg/mL
  10. PI-3065
    B4660 PI-3065
    Target: PI3K
    Summary: P110δkinase inhibitor
      ≥22.7 mg/mL

Items 11-20 of 21

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