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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

A3014 BGJ398

1 Citation

Target: FGFR

Summary: FGFR inhibitor ,potent and selective

insoluble in H2O; insoluble in EtOH; ≥7 mg/mL
A3022 Pazopanib (GW-786034)

Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
A4116 Danusertib (PHA-739358)

2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL
A8706 BLU9931

Target: FGFR

Summary: FGFR4 inhibitor,potent and irreversible

≥50.9 mg/mL
B4985 CH5183284 (Debio-1347)

Summary: selective and orally available FGFR inhibitor

≥35.6 mg/mL
B4904 ACTB-1003

Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K

Summary: FGFR1 inhibitor

insoluble in H2O; ≥18.15 mg/mL
B7486 PD 161570

Summary: FGFR inhibitor

<53.25 mg/mL