Tamibarotene
Catalog No.
A3856
RARα agonist
Featured Products
Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 351.44 |
| Cas No. | 94497-51-5 |
| Formula | C22H25NO3 |
| Synonyms | Am80;Am 80;Am-80 |
| Solubility | insoluble in H2O; ≥13.35 mg/mL in DMSO; ≥52.5 mg/mL in EtOH with ultrasonic |
| Chemical Name | 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid |
| SDF | Download SDF |
| Canonical SMILES | CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
