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UNC0379

Catalog No.
B8009
N-lysine methyltransferase SETD8 inhibitor
Grouped product items
Size Price Stock Qty
5mg
Special Price $37.35 Regular Price $83.00
Ship with 10-15 days
10mg
Special Price $49.50 Regular Price $110.00
Ship with 10-15 days
50mg
Special Price $150.75 Regular Price $335.00
Ship with 10-15 days
100mg
Special Price $216.00 Regular Price $480.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM; selective over 15 other methyltransferases.

Chemical Properties

Physical AppearanceA crystalline solid
StorageDesiccate at -20°C
M.Wt413.56
Cas No.1620401-82-2
FormulaC23H35N5O2
SolubilitySoluble in DMSO
Chemical Name6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(N=C(N2CCCC2)N=C3NCCCCCN4CCCC4)C3=C1)OC
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

UNC0379