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Arctigenin

Catalog No.
N2399
Anti-inflammatory, antiproliferative
Grouped product items
Size Price Stock Qty
10mM (in 1mL DMSO)
Special Price $22.50 Regular Price $50.00
In stock
20mg
Special Price $30.15 Regular Price $67.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Antioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation (IC50 = 10 nM). Inhibits HIV-1 replication in vitro. Also potently inhibits MKK1 (MEK1) (IC50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.

Chemical Properties

Physical AppearanceA solid
StorageDesiccate at -20°C
M.Wt372.41
Cas No.7770-78-7
FormulaC21H24O6
Synonyms(-)-Arctigenin
Solubilityinsoluble in H2O; insoluble in EtOH; ≥17.2 mg/mL in DMSO
Chemical Name(3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
SDFDownload SDF
Canonical SMILESO=C1OC[C@H](CC2=CC=C(OC)C(OC)=C2)[C@H]1CC(C=C3OC)=CC=C3O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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