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JK 184

Catalog No.
A8652
Hh signaling inhibitor
Grouped product items
Size Price Stock Qty
5mg
Special Price $36.00 Regular Price $80.00
Ship with 10-15 days
10mg
Special Price $54.45 Regular Price $121.00
Ship with 10-15 days
50mg
Special Price $216.90 Regular Price $482.00
Ship with 10-15 days
100mg
Special Price $387.00 Regular Price $860.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 - 21 nM) and in human xenografts in vivo. Inhibits alcoh

Chemical Properties

Physical AppearanceA pale pink to off-white solid
StorageStore at -20°C
M.Wt350.44
Cas No.315703-52-7
FormulaC19H18N4OS
SolubilitySoluble in DMSO
Chemical NameN-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
SDFDownload SDF
Canonical SMILESCCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

JK 184