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IκB/IKK

IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.

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  1. Wedelolactone
    N2131 Wedelolactone
    Summary: IKK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥44.4 mg/mL
  2. Piceatannol
    N2031 Piceatannol
    Summary: p56lck/Syk inhibitor
      insoluble in H2O; ≥12.2 mg/mL
  3. Celastrol
    A2604 Celastrol
    Target: Proteasome
    Summary: Antioxidant, anti-inflammatory and immunosuppressive agent
      ≥22.55 mg/mL
  4. IKK-16 (IKK Inhibitor VII)
    B1586 IKK-16 (IKK Inhibitor VII)
     1 Citation
    Summary: Selective IκB kinase inhibitor
      ≥23.05 mg/mL
  5. TPCA-1
    A4602 TPCA-1
     2 Citation
    Summary: IKK-2 inhibitor,potent and selective
      insoluble in H2O; ≥13.95 mg/mL
  6. PS-1145
    B6089 PS-1145
    Summary: IKK inhibitor
      ≥32.3 mg/mL
  7. LY2409881
    B4986 LY2409881
    Summary: potent and selective IKK2 inhibitor
      ≥59.4 mg/mL
  8. IKK-16 (hydrochloride)
    C4569 IKK-16 (hydrochloride)
    Summary: IκB kinases (IKKs) inhibitor
      ≤10 mg/mL
  9. ML 120B dihydrochloride
    B5756 ML 120B dihydrochloride
    Summary: IKK2-selective inhibitor
      ≥44 mg/mL
  10. WS6
    B4880 WS6
    Summary: inducer of β cell proliferation

Items 21-30 of 35

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