IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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B1587 IMD 03541 CitationSummary: IKKβ inhibitor -
B1585 SC-514Summary: ATP-competitive IKK-2 inhibitor, orally active
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N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent
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A2604 CelastrolTarget: ProteasomeSummary: Antioxidant, anti-inflammatory and immunosuppressive agent