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IκB/IKK

IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.

9 Items

per page
  1. IKK-2 inhibitor VIII
    A3485 IKK-2 inhibitor VIII
    Summary: IKK-2 inhibitor,potent and selective
      Soluble in DMSO
  2. QNZ (EVP4593)
    A4217 QNZ (EVP4593)
     2 Citation
    Summary: Potent NF-κB inhibitor
  3. BMS345541 hydrochloride
    A3248 BMS345541 hydrochloride
    Target: IKK
    Summary: IKK inhibitor,highly selective
      insoluble in EtOH; insoluble in DMSO; ≥60 mg/mL
  4. IMD 0354
    B1587 IMD 0354
     1 Citation
    Summary: IKKβ inhibitor
      insoluble in H2O; ≥100.8 mg/mL
  5. SC-514
    B1585 SC-514
    Summary: ATP-competitive IKK-2 inhibitor, orally active
      insoluble in EtOH; insoluble in H2O; ≥50.4 mg/mL
  6. Luteolin
    N1831 Luteolin
    Target: AP-1|MMP|15-lipoxygenases
    Summary: Antioxidant and free radical scavenger
  7. Tanshinone IIA
    N1846 Tanshinone IIA
    Target: AP-1|MAGL
    Summary: Antioxidant and anti-inflammatory reagent
      insoluble in EtOH; insoluble in H2O; ≥3.42 mg/mL
  8. Celastrol
    A2604 Celastrol
    Target: Proteasome
    Summary: Antioxidant, anti-inflammatory and immunosuppressive agent
      ≥22.55 mg/mL
  9. BMS-345541(free base)
    B4655 BMS-345541(free base)
    Summary: IKK-1/IKK-2 inhibitor,potent and selective
      insoluble in H2O; ≥70 mg/mL

9 Items

per page