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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Items 31-40 of 41

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  1. AEE788 (NVP-AEE788)
    A5455 AEE788 (NVP-AEE788)
    Summary: EGFR/HER-2/VEGFR inhibitor
      ≥22.05 mg/mL
  2. PD168393
    A2024 PD168393
    Target: PDGFR|FGFR|EGFR|PKC|insulin
    Summary: EGFR inhibitor
  3. AG-18
    A1173 AG-18
    Summary: EGFR/PDGFR inhibitor
  4. Butein
    A2689 Butein
    Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase
    Summary: Protein kinase inhibitor
      insoluble in H2O; ≥13.6 mg/mL
  5. ALK-IN-1
    A1367 ALK-IN-1
    Summary: Anaplastic lymphoma kinase (ALK) inhibitor
      ≥26.45 mg/mL
  6. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  7. Neratinib (HKI-272)
    A8322 Neratinib (HKI-272)
     1 Citation
    Target: EGFR
    Summary: HER2/EGFR inhibitor,potent and irreversible
      insoluble in H2O; ≥13.93 mg/mL
  8. AG-1478
    A8357 AG-1478
    Target: EGFR
    Summary: EGFR inhibitor,potent and selective
      insoluble in H2O; ≥15.8 mg/mL
  9. RG 13022
    B6115 RG 13022
    Summary: EGFR tyrosine kinase inhibitor
      ≥26.6 mg/mL
  10. AZ5104
    B5836 AZ5104
    Target: EGFR
    Summary: EGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL

Items 31-40 of 41

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