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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

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  1. WAY-600
    B1641 WAY-600
    Target: mTOR
    Summary: MTOR inhibitor
      ≥12.38 mg/mL
  2. Rapamycin (Sirolimus)
    A8167 Rapamycin (Sirolimus)
     15 Citation
    Target: mTOR
    Summary: Original antifungal antibiotic
      ≥45.7 mg/mL
  3. Everolimus (RAD001)
    A8169 Everolimus (RAD001)
     8 Citation
    Target: mTOR
    Summary: MTOR inhibitor
      ≥47.91 mg/mL
  4. CC-223
    B6171 CC-223
    Summary: mTOR inhibitor, orally bioavailable
      insoluble in H2O; ≥108 mg/mL
  5. MHY1485
    B5853 MHY1485
     2 Citation
    Target: mTOR
    Summary: mTOR activator, autophage inhibitor
      insoluble in EtOH; insoluble in H2O; ≥19.35 mg/mL
  6. OXA-01
    C4204 OXA-01
    Summary: mTORC1 and mTORC2 inhibitor
      ≤3 mg/mL
  7. GNE-493
    B8000 GNE-493
    Summary: Pan-PI3K/mTOR inhibitor
      Soluble in DMSO
  8. GNE-477
    B8001 GNE-477
    Summary: dual PI3K/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL
  9. Rapalink-1
    A8764 Rapalink-1
    Target: mTOR
    Summary: third-generation mTOR inhibitor
      ≥178.4 mg/mL

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