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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 21-30 of 62

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  1. PKI-402
    A8505 PKI-402
    Summary: PI3K inhibitor,selective, reversible and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥14.28 mg/mL
  2. Quercetin
    N1841 Quercetin
    Summary: Antitumor agent
      insoluble in H2O; ≥15.1 mg/mL
  3. CAL-101 (Idelalisib, GS-1101)
    A3005 CAL-101 (Idelalisib, GS-1101)
     2 Citation
    Target: PI3K
    Summary: PI3K inhibitor
  4. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  5. PP121
    B2172 PP121
    Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck
    Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
  6. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  7. GDC-0941
    A8210 GDC-0941
     10 Citation
    Target: PI3K
    Summary: PI3K inhibitor,potent and selective
      ≥25.7 mg/mL
  8. BEZ235 (NVP-BEZ235)
    A8246 BEZ235 (NVP-BEZ235)
     2 Citation
    Summary: PI3K/mTOR inhibitor,ATP-competitve
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  9. ZSTK474
    A8248 ZSTK474
    Summary: Potent PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.85 mg/mL
  10. LY 294002
    A8250 LY 294002
     16 Citation
    Target: PI3K
    Summary: Potent PI3K inhibitor

Items 21-30 of 62

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