Signaling Pathways
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A5618 Daclatasvir (BMS-790052)Target: HCV ProteasesSummary: HCV NS5A inhibitor
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A5634 SAR245409 (XL765)Summary: mTOR/PI3K inhibitor
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A5639 BIRB 796 (Doramapimod)1 CitationSummary: P38 MAPK inhibitor,cell permeable and highly selective
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A5653 AT7867Target: Akt|PKA|p70 rskSummary: Akt1/2/3 and p70S6K/PKA inhibitor
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A5700 BS-181 HClTarget: Cyclin-Dependent KinasesSummary: CDK7 inhibitor,highly selective
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A5703 BMS-777607Target: METSummary: C-Met inhibitor, potent and selective
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A5707 PD318088Target: MEKSummary: Allosteric MEK1/2 inhibitor, non-ATP competitive
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A5719 AT7519Target: Cyclin-Dependent KinasesSummary: Multi-CDK inhibitor
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A5734 Fasudil (HA-1077) HCl1 CitationTarget: ROCKSummary: Protein kinase inhibitor
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A5755 MK-17752 CitationSummary: Wee1 kinase inhibtor,potent and ATP-competitive